Most skin boosters rely on hyaluronic acid alone. LongevHA combines five bioactive ingredients, dual-weight HA, NAD+, Resveratrol, Mannitol, and peptides, to support skin health at the cellular level, targeting hydration, collagen production, antioxidant protection, and cellular energy simultaneously.
Pick up almost any skin booster brochure and you’ll see the same promise: deep hydration, improved elasticity, a natural glow. Standard HA-based boosters do deliver on these claims, to a degree. But hydration alone doesn’t address why skin loses its vitality as we age. LongevHA was formulated with that question in mind.
What does a traditional skin booster actually contain?
Most skin boosters on the market are built around a single active ingredient: hyaluronic acid. HA is a naturally occurring molecule found in the skin that attracts and binds water, helping maintain moisture and suppleness. Injecting HA directly into the dermis floods the skin with hydration from within, more effectively than any topical moisturizer can.
The results are real, but they’re largely limited to hydration and the indirect benefits that follow, such as improved plumpness and a reduction in the appearance of fine lines caused by dehydration.
What makes LongevHA’s “Big 5” formula different?
LongevHA uses five ingredients, each selected for a specific function:
1. Dual-weight hyaluronic acid (32 mg/ml)
LongevHA contains both high- and low-molecular-weight HA. High-molecular-weight HA sits in the upper layers of the dermis, providing structural support and surface hydration. Low-molecular-weight HA penetrates deeper, delivering moisture and signaling benefits at a more cellular level. Together, they provide more comprehensive hydration than a single-weight HA can achieve.
2. NAD+ (Nicotinamide Adenine Dinucleotide)
NAD+ is a coenzyme present in every living cell, essential for hundreds of biological processes, including energy metabolism and DNA repair. NAD+ acts as a “battery charger” for skin cells, helping to activate sirtuin proteins (particularly Sirt1, often called the “longevity gene”). This sirtuin activation is designed to support cellular renewal and help skin cells function more efficiently, contributing to what Dr. Adams Aesthetics describes as a “time-reverse effect.”
3. Resveratrol
Resveratrol is a polyphenol with well-documented antioxidant properties. Delivered directly into the skin via injection, Resveratrol helps defend against oxidative stress, one of the key drivers of visible skin aging. Resveratrol also works synergistically with NAD+ to support sirtuin activation.
4. Mannitol
Mannitol serves two critical, synergistic roles within LongevHA. First, it acts as a potent free-radical scavenger; by reducing oxidative stress and neutralizing reactive oxygen species (ROS), it shields the hyaluronic acid from premature degradation, thereby prolonging its hydrating and visible effects. Second, mannitol’s anti-inflammatory properties mitigate the local inflammatory response to reduce transient post-injection swelling. The combined result is an enhanced product longevity and a significantly smoother, more comfortable recovery period for the patient.
5. Peptides
Peptides are short chains of amino acids that act as messengers in the skin, signaling cells to produce more collagen and elastin. Including peptides in LongevHA’s formula supports structural improvement over time, not just surface-level hydration.
What does the combined effect look like?
A standard HA booster addresses dehydration. LongevHA is designed to support skin quality across multiple dimensions simultaneously: hydration, cellular energy, antioxidant protection, collagen stimulation, and HA longevity. The formula works synergistically, each ingredient supports and amplifies the others.
For patients noticing dullness, fine lines, uneven texture, or skin that simply looks tired, this multi-ingredient approach is designed to target the appearance of cellular fatigue in ways that a single-ingredient booster cannot.
Want to experience the NAD+ difference? Ask your local aesthetics provider for LongevHA at your next consultation, or visit our Find a Provider page to find a trained practitioner near you.
Frequently Asked Questions
What are the five key ingredients in LongevHA?
LongevHA’s “Big 5” formula includes dual-weight hyaluronic acid (32 mg/ml), NAD+, Resveratrol, Mannitol, and peptides. Each ingredient supports a distinct aspect of skin health, from hydration and collagen production to antioxidant defense and cellular energy.
Why does LongevHA use dual-weight hyaluronic acid?
Dual-weight HA allows LongevHA to hydrate at multiple depths within the skin. High-molecular-weight HA supports structural hydration in the upper dermis, while low-molecular-weight HA penetrates deeper to deliver hydration and cellular signaling benefits. In total, LongevHA has 80 mg of HA in two molecular weights (40 mg + 40 mg).
What does NAD+ do in a skin booster?
NAD+ is a coenzyme that supports cellular energy production and DNA repair. In LongevHA, NAD+ is designed to activate sirtuin proteins, which support cellular renewal and help skin cells function more efficiently, contributing to what Dr. Adams Aesthetics calls a “time-reverse effect.”
How is LongevHA different from other skin boosters like Profhilo or Juvederm Volite?
Unlike many skin boosters that rely solely on HA, LongevHA adds NAD+, Resveratrol, Mannitol, and peptides to support skin health at the cellular level. This multi-ingredient approach is designed to address hydration, cellular energy, antioxidant protection, and collagen stimulation simultaneously.